SUFUH Antikörper (AA 325-484)
Kurzübersicht für SUFUH Antikörper (AA 325-484) (ABIN6148692)
Target
Alle SUFUH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 325-484
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Sequenz
- PPINPQRQNG LAHDRAPSRK DSLESDSSTA IIPHELIRTR QLESVHLKFN QESGALIPLC LRGRLLHGRH FTYKSITGDM AITFVSTGVE GAFATEEHPY AAHGPWLQIL LTEEFVEKML EDLEDLTSPE EFKLPKEYSW PEKKLKVSIL PDVVFDSPLH
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 325-484 of human SUFU (NP_057253.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- SUFUH (Suppressor of Fused Homolog (SUFUH))
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Andere Bezeichnung
- SUFU
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Hintergrund
- The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.,SUFU,PRO1280,SUFUH,SUFUXL,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Hedgehog Signaling Pathway,SUFU
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Molekulargewicht
- 47 kDa/52 kDa/53 kDa
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Gen-ID
- 51684
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UniProt
- Q9UMX1
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Pathways
- Hedgehog Signalweg, Tube Formation, Maintenance of Protein Location
Target
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