beta Amyloid Antikörper (C-Term)

Produktnummer ABIN614817

Der Maus Monoklonal anti-beta Amyloid Antikörper (Klon CV9 7B10) (ABIN614817) detektiert spezifisch beta Amyloid in EIA und ELISA (Detection). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für beta Amyloid Antikörper (C-Term) (ABIN614817)

Target: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser beta Amyloid Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), ELISA (Detection)

Klon: CV9 7B10

Produktdetails anti-beta Amyloid Antikörper

Bindungsspezifität: C-Term

Sequenz: GLMVGGVV

Spezifität: This antibody recognizes the C-terminal peptide of beta amyloid peptide 40, and full length beta amyloid peptide 40.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein G affinity chromatography

Immunogen: C-terminal amino acid sequence of human beta amyloid peptide 40, conjugated with KLH

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with Double distillated water is recommended to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store (in aliquots) at -20 °C.

Details zu beta Amyloid

Target: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Andere Bezeichnung: Amyloid beta

Hintergrund: Aβ40, Aβ42 and Aβ43 are different only at the few C-end amino acids. While the C-end amino acids showed no speciesspecificity in mammalians, the Nterminal amino acid sequences have minor discrepancies between difference species. Amyloid beta peptides Aβ42 and Aβ40 have been investigated extensively for predicating Alzheimer's disease. A recent study on A Aβ43 in brain showed that Aβ43 is more fibrillogenic than the other amyloid beta peptides and may be useful as a biomarker or therapeutic target for Alzheimer's disease. Antibody to N-terminal sequence can bind to all the three amyloid beta peptides.

Gen-ID: 351

Pathways: Inflammasome