SETDB2
Reaktivität: Ratte
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 680
Applikationshinweise
WB,1:500 - 1:2000,IF,1:50 - 1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
SETDB2
(SET Domain, Bifurcated 2 (SETDB2))
Andere Bezeichnung
SETDB2
Hintergrund
This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants.,SETDB2,C13orf4,CLLD8,CLLL8,KMT1F,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,SETDB2