S1PR1 Antikörper (AA 303-382)

Produktnummer ABIN6147349

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch S1PR1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für S1PR1 Antikörper (AA 303-382) (ABIN6147349)

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S1PR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-S1PR1 Antikörper

Bindungsspezifität: AA 303-382

Sequenz: NSGTNPIIYT LTNKEMRRAF IRIMSCCKCP SGDSAGKFKR PIIAGMEFSR SKSDNSSHPQ KDEGDNPETI MSSGNVNSSS

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 303-382 of human EDG1/HEXIM1 (NP_001391.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu S1PR1

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Andere Bezeichnung: S1P1/EDG1

Hintergrund: The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.,S1PR1,CD363,CHEDG1,D1S3362,ECGF1,EDG-1,EDG1,S1P1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Apoptosis,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Immunology & Inflammation,CD markers,Cardiovascular,Angiogenesis,S1P1/EDG1

Molekulargewicht: 42 kDa

Gen-ID: 1901

UniProt: P21453

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2