RORC Antikörper (AA 120-320)

Produktnummer ABIN6147079

Produktdetails anti-RORC Antikörper

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Bindungsspezifität: AA 120-320

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RORC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KQLQQRQQQQ QEPVVKTPPA GAQGADTLTY TLGLPDGQLP LGSSPDLPEA SACPPGLLKA SGSGPSYSNN LAKAGLNGAS CHLEYSPERG KAEGRESFYS TGSQLTPDRC GLRFEEHRHP GLGELGQGPD SYGSPSFRST PEAPYASLTE IEHLVQSVCK SYRETCQLRL EDLLRQRSNI FSREEVTGYQ RKSMWEMWER C

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-320 of human RORC (NP_005051.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RORC

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Andere Bezeichnung: RORC (RORC Produkte)

Hintergrund: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.,RORC,IMD42,NR1F3,RORG,RZR-GAMMA,RZRG,TOR,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,RORC

Molekulargewicht: 55 kDa/58 kDa

Gen-ID: 6097

UniProt: P51449

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway