RIN2 Antikörper (AA 596-895)

Produktnummer ABIN6146954

Dieses Anti-RIN2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RIN2 in WB. Geeignet für Human.

Kurzübersicht für RIN2 Antikörper (AA 596-895) (ABIN6146954)

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RIN2 Antikörper

Bindungsspezifität: AA 596-895

Sequenz: HKCILKPLKG HVEAMLKDFH MADGSWKQLK ENLQLVRQRN PQELGVFAPT PDFVDVEKIK VKFMTMQKMY SPEKKVMLLL RVCKLIYTVM ENNSGRMYGA DDFLPVLTYV IAQCDMLELD TEIEYMMELL DPSLLHGEGG YYLTSAYGAL SLIKNFQEEQ AARLLSSETR DTLRQWHKRR TTNRTIPSVD DFQNYLRVAF QEVNSGCTGK TLLVRPYITT EDVCQICAEK FKVGDPEEYS LFLFVDETWQ QLAEDTYPQK IKAELHSRPQ PHIFHFVYKR IKNDPYGIIF QNGEEDLTTS

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 596-895 of human RIN2 (NP_061866.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RIN2

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Andere Bezeichnung: RIN2

Hintergrund: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.,RIN2,MACS,RASSF4,Signal Transduction,G protein signaling,Signal Transduction,RIN2

Molekulargewicht: 100 kDa/105 kDa

Gen-ID: 54453

UniProt: Q8WYP3