REST Antikörper (AA 760-1060)

Produktnummer ABIN6146870

Dieses Anti-REST-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von REST in WB. Geeignet für Human.

Kurzübersicht für REST Antikörper (AA 760-1060) (ABIN6146870)

Target: REST (RE1-Silencing Transcription Factor (REST))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser REST Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-REST Antikörper

Bindungsspezifität: AA 760-1060

Sequenz: PVKIELSPPI EVVQKEPVQM ELSPPMGVVQ KEPAQREPPP PREPPLHMEP ISKKPPLRKD KKEKSNMQSE RARKEQVLIE VGLVPVKDSW LLKESVSTED LSPPSPPLPK ENLREEASGD QKLLNTGEGN KEAPLQKVGA EEADESLPGL AANINESTHI SSSGQNLNTP EGETLNGKHQ TDSIVCEMKM DTDQNTRENL TGINSTVEEP VSPMLPPSAV EEREAVSKTA LASPPATMAA NESQEIDEDE GIHSHEGSDL SDNMSEGSDD SGLHGARPVP QESSRKNAKE ALAVKAAKGD F

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 760-1060 of human REST/NRSF (NP_001180437.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu REST

Target: REST (RE1-Silencing Transcription Factor (REST))

Andere Bezeichnung: REST

Hintergrund: This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described,REST,NRSF,WT6,XBR,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,Neurodegenerative Diseases,REST

Molekulargewicht: 35 kDa/36 kDa/119 kDa/121 kDa

Gen-ID: 5978

UniProt: Q13127

Pathways: Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity