A2BP1 Antikörper (AA 1-130)

Produktnummer ABIN6146754

Der Kaninchen Polyklonal Anti-A2BP1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, A2BP1 in Proben von Human zu detektieren.

Kurzübersicht für A2BP1 Antikörper (AA 1-130) (ABIN6146754)

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser A2BP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-A2BP1 Antikörper

Bindungsspezifität: AA 1-130

Sequenz: MLASQGVLLH PYGVPMIVPA APYLPGLIQG NQEAAAAPDT MAQPYASAQF APPQNGIPAE YTAPHPHPAP EYTGQTTVPE HTLNLYPPAQ THSEQSPADT SAQTVSGTAT QTDDAAPTDG QPQTQPSENT

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human RBFOX1 (NP_665900.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu A2BP1

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Andere Bezeichnung: RBFOX1

Hintergrund: The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.,RBFOX1,2BP1,A2BP1,FOX-1,FOX1,HRNBP1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Neuroscience,Neurodegenerative Diseases,RBFOX1

Molekulargewicht: 40 kDa/42 kDa/44 kDa

Gen-ID: 54715

UniProt: Q9NWB1