A2BP1 Antikörper (N-Term)

Produktnummer ABIN2779139

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-A2BP1 Antikörper wird verwendet zum Nachweis von A2BP1 in Proben von Human, Ratte, Maus, Rind (Kuh), Hund, Pferd und Meerschweinchen. Er wurde validiert für WB.

Kurzübersicht für A2BP1 Antikörper (N-Term) (ABIN2779139)

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser A2BP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-A2BP1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Rbfox1 Antibody - N-terminal region

Sequenz: EYTGQTTVPD HTLNLYPPTQ THSEQSADTS AQTVSGTATQ TDDAAPTDGQ

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Rbfox1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Rbfox1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40920-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-A2BP1 Antikörper (ABIN2779139)

Fogel, Wexler, Wahnich, Friedrich, Vijayendran, Gao, Parikshak, Konopka, Geschwind: "RBFOX1 regulates both splicing and transcriptional networks in human neuronal development." in: Human molecular genetics, Vol. 21, Issue 19, pp. 4171-86, (2012) (PubMed).

Details zu A2BP1

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Andere Bezeichnung: Rbfox1

Hintergrund:

Background Information: Rbfox1 is a RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. It prevents binding of U2AF2 to the 3'-splice site and regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.

Alternative Symbols: A2, A2b, FOX, HRN, A2bp, A2bp1, fox-1, Hrnbp1

Protein Name: RNA binding protein fox-1 homolog 1

Molekulargewicht: 43kDa

Gen-ID: 268859

NCBI Accession: NP_067452

UniProt: Q9JJ43