PUM1 Antikörper (AA 1-130)

Produktnummer ABIN6146494

Der Kaninchen Polyklonal Anti-PUM1-Antikörper wurde für WB und IF validiert. Er ist geeignet, PUM1 in Proben von Human zu detektieren.

Kurzübersicht für PUM1 Antikörper (AA 1-130) (ABIN6146494)

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PUM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-PUM1 Antikörper

Bindungsspezifität: AA 1-130

Sequenz: MSVACVLKRK AVLWQDSFSP HLKHHPQEPA NPNMPVVLTS GTGSQAQPQP AANQALAAGT HSSPVPGSIG VAGRSQDDAM VDYFFQRQHG EQLGGGGSGG GGYNNSKHRW PTGDNIHAEH QVRSMDELNH

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human Pumilio 1 (NP_055491.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PUM1

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Andere Bezeichnung: pum1

Hintergrund: This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.,PUM1,HSPUM,PUMH,PUMH1,PUML1,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Stem Cells,Germline Stem Cells,pum1

Molekulargewicht: 119 kDa/124 kDa/126 kDa

Gen-ID: 9698

UniProt: Q14671