PTPRD Antikörper (AA 475-574)

Produktnummer ABIN6146458

Produktdetails anti-PTPRD Antikörper

Target: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Bindungsspezifität: AA 475-574

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPRD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: QITTIGNLVP QKTYSVKVLA FTSIGDGPLS SDIQVITQTG VPGQPLNFKA EPESETSILL SWTPPRSDTI ANYELVYKDG EHGEEQRITI EPGTSYRLQG

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 475-574 of human PTPRD (NP_002830.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PTPRD

Target: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Andere Bezeichnung: PTPRD (PTPRD Produkte)

Hintergrund: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.,PTPRD,HPTP,HPTPD,HPTPDELTA,PTPD,RPTPDELTA,Signal Transduction,Neuroscience,PTPRD

Molekulargewicht: 156 kDa/169 kDa/212 kDa/214 kDa

Gen-ID: 5789

UniProt: P23468

Pathways: Synaptic Membrane