ADRP Antikörper (AA 168-437)

Produktnummer ABIN6145773

Der Kaninchen Polyklonal Anti-ADRP-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, ADRP in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für ADRP Antikörper (AA 168-437) (ABIN6145773)

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ADRP Antikörper

Bindungsspezifität: AA 168-437

Sequenz: MMQLVSSGVE NALTKSELLV EQYLPLTEEE LEKEAKKVEG FDLVQKPSYY VRLGSLSTKL HSRAYQQALS RVKEAKQKSQ QTISQLHSTV HLIEFARKNV YSANQKIQDA QDKLYLSWVE WKRSIGYDDT DESHCAEHIE SRTLAIARNL TQQLQTTCHT LLSNIQGVPQ NIQDQAKHMG VMAGDIYSVF RNAASFKEVS DSLLTSSKGQ LQKMKESLDD VMDYLVNNTP LNWLVGPFYP QLTESQNAQD QGAEMDKSSQ ETQRSEHKTH

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 168-437 of human Perilipin-2 (NP_001113.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-ADRP Antikörper (ABIN6145773)

Ni, He, Dai, Yao, Guo, Wei: "Oroxylin A suppresses the development and growth of colorectal cancer through reprogram of HIF1α-modulated fatty acid metabolism." in: Cell death & disease, Vol. 8, Issue 6, pp. e2865, (2018) (PubMed).

Cao, Ruan, Wang, Song, Bao, Xu, Xiao, Wang, Cheng, Tong, Meng, Liu, Yang, Chen, Zhang: "Overexpression of PLIN2 is a prognostic marker and attenuates tumor progression in clear cell renal cell carcinoma." in: International journal of oncology, Vol. 53, Issue 1, pp. 137-147, (2018) (PubMed).

Details zu ADRP

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Andere Bezeichnung: PLIN2

Hintergrund: The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.,PLIN2,ADFP,ADRP,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Hypoxia,Hypoxia-Regulated,Heart,Lipids,Adipose Related,Cardiovascular diseases,Heart disease,PLIN2

Molekulargewicht: 48 kDa

Gen-ID: 123

UniProt: Q99541

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism