PIAS3 Antikörper (AA 399-628)

Produktnummer ABIN6145598

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PIAS3 in IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PIAS3 Antikörper (AA 399-628) (ABIN6145598)

Target: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIAS3 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktdetails anti-PIAS3 Antikörper

Bindungsspezifität: AA 399-628

Sequenz: FMEDGSWCPM KPKKEASEVC PPPGYGLDGL QYSPVQGGDP SENKKKVEVI DLTIESSSDE EDLPPTKKHC SVTSAAIPAL PGSKGVLTSG HQPSSVLRSP AMGTLGGDFL SSLPLHEYPP AFPLGADIQG LDLFSFLQTE SQHYGPSVIT SLDEQDALGH FFQYRGTPSH FLGPLAPTLG SSHCSATPAP PPGRVSSIVA PGGALREGHG GPLPSGPSLT GCRSDIISLD

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 399-628 of human PIAS3 (NP_006090.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PIAS3

Target: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Andere Bezeichnung: PIAS3

Hintergrund: This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.,PIAS3,ZMIZ5,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,PIAS3

Molekulargewicht: 68 kDa

Gen-ID: 10401

UniProt: Q9Y6X2

Pathways: JAK-STAT Signalweg