PFKFB2 Antikörper (AA 446-505)

Produktnummer ABIN6145483

Dieses Anti-PFKFB2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PFKFB2 in WB und IF. Geeignet für Human.

Kurzübersicht für PFKFB2 Antikörper (AA 446-505) (ABIN6145483)

Target: PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFKFB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-PFKFB2 Antikörper

Bindungsspezifität: AA 446-505

Sequenz: RDKPTNNFPK NQTPVRMRRN SFTPLSSSNT IRRPRNYSVG SRPLKPLSPL RAQDMQEGAD

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 446-505 of human PFKFB2 (NP_006203.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PFKFB2

Target: PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))

Andere Bezeichnung: PFKFB2

Hintergrund: The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.,PFKFB2,PFK-2/FBPase-2,Signal Transduction,PI3K-Akt Signaling Pathway,Endocrine & Metabolism,Carbohydrate metabolism,Warburg Effect,PFKFB2

Molekulargewicht: 54 kDa/58 kDa

Gen-ID: 5208

UniProt: O60825

Pathways: PI3K-Akt Signalweg, Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process