NRARP Antikörper (AA 1-114)

Produktnummer ABIN6144838

Dieses Anti-NRARP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NRARP in WB. Geeignet für Human.

Kurzübersicht für NRARP Antikörper (AA 1-114) (ABIN6144838)

Target: NRARP (NOTCH-Regulated Ankyrin Repeat Protein (NRARP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NRARP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NRARP Antikörper

Bindungsspezifität: AA 1-114

Sequenz: MSQAELSTCS APQTQRIFQE AVRKGNTQEL QSLLQNMTNC EFNVNSFGPE GQTALHQSVI DGNLELVKLL VKFGADIRLA NRDGWSALHI AAFGGHQDIV LYLITKAKYA ASGR

Kreuzreaktivität: Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human NRARP (NP_001004354.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NRARP

Target: NRARP (NOTCH-Regulated Ankyrin Repeat Protein (NRARP))

Andere Bezeichnung: NRARP

Hintergrund: Downstream effector of Notch signaling. Involved in the regulation of liver cancer cells self-renewal. Involved in angiogenesis acting downstream of Notch at branch points to regulate vascular density. Proposed to integrate endothelial Notch and Wnt signaling to control stalk cell proliferation and to stablilize new endothelial connections during angiogenesis. During somitogenesis involved in maintenance of proper somite segmentation and proper numbers of somites and vertebrae. Required for proper anterior-posterior somite patterning. Proposed to function in a negative feedback loop to destabilize Notch 1 intracellular domain (NICD and downregulate the Notch signal, preventing expansion of the Notch signal into the anterior somite domain (By similarity.,NRARP,Cell Biology & Developmental Biology,Neuroscience,Cardiovascular,Angiogenesis,NRARP

Molekulargewicht: 12 kDa

Gen-ID: 441478

UniProt: Q7Z6K4