NOTCH4 Antikörper (AA 1824-2003)

Produktnummer ABIN6144740

Dieses Anti-NOTCH4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NOTCH4 in WB und IF. Geeignet für Human.

Kurzübersicht für NOTCH4 Antikörper (AA 1824-2003) (ABIN6144740)

Target: NOTCH4 (Notch 4 (NOTCH4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOTCH4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-NOTCH4 Antikörper

Bindungsspezifität: AA 1824-2003

Sequenz: PPEARHKATP GREAGPFPRA RTVSVSVPPH GGGALPRCRT LSAGAGPRGG GACLQARTWS VDLAARGGGA YSHCRSLSGV GAGGGPTPRG RRFSAGMRGP RPNPAIMRGR YGVAAGRGGR VSTDDWPCDW VALGACGSAS NIPIPPPCLT PSPERGSPQL DCGPPALQEM PINQGGEGKK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1824-2003 of human NOTCH4 (NP_004548.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NOTCH4

Target: NOTCH4 (Notch 4 (NOTCH4))

Andere Bezeichnung: NOTCH4

Hintergrund: This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,NOTCH4,INT3,notch 4,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,Notch Signaling Pathway,ESC Pluripotency and Differentiation,Stem Cells,Cardiovascular,Angiogenesis,Heart,Cardiogenesis,NOTCH4

Molekulargewicht: 39 kDa/61 kDa/209 kDa

Gen-ID: 4855

UniProt: Q99466

Pathways: Notch Signalweg