Integrin beta 4 Antikörper
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- Target Alle Integrin beta 4 (ITGB4) Antikörper anzeigen
- Integrin beta 4 (ITGB4)
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Reaktivität
- Human
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser Integrin beta 4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- Recognizes Integrin Beta 4 (ITGB4).
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Aufreinigung
- Affinity Chromatography.
- Immunogen
- Human ITGB4
- Klon
- 439-9B
- Isotyp
- IgG2b
- Top Product
- Discover our top product ITGB4 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- PBS, pH 7.2 containing < / = 0.09 % Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C.
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- Target
- Integrin beta 4 (ITGB4)
- Andere Bezeichnung
- CD104 / Integrin beta-4 (ITGB4 Produkte)
- Hintergrund
- Integrins are heterodimers composed of noncovalently associated transmembrane alpha and beta subunits. The 16 alpha and 8 beta subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors, both receptor clustering and ligand occupancy are necessary for the activation of integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.Synonyms: GP150, ITGB4
- Gen-ID
- 3691
- NCBI Accession
- NP_000204
- UniProt
- P16144
- Pathways
- Integrin Complex
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