MRGPRX1 Antikörper (AA 263-322)
Kurzübersicht für MRGPRX1 Antikörper (AA 263-322) (ABIN6143996)
Target
Alle MRGPRX1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 263-322
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Sequenz
- LNSSANPIIY FFVGSFRQRQ NRQNLKLVLQ RALQDASEVD EGGGQLPEEI LELSGSRLEQ
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Kreuzreaktivität
- Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 263-322 of human MRGPRX1 (NP_671732.3).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))
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Andere Bezeichnung
- MRGPRX1
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Hintergrund
- Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22 and BAM (8-22(PubMed:26582731. BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alphaq proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.,MRGPRX1,GPCR,MGRG2,MRGX1,SNSR4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),MRGPRX1
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Molekulargewicht
- 36 kDa
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Gen-ID
- 259249
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UniProt
- Q96LB2
Target
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