SMCR7L Antikörper (AA 40-280)

Produktnummer ABIN6143839

Produktdetails anti-SMCR7L Antikörper

Target: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Bindungsspezifität: AA 40-280

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMCR7L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GIATLAVKRM YDRAISAPTS PTRLSHSGKR SWEEPNWMGS PRLLNRDMKT GLSRSLQTLP TDSSTFDTDT FCPPRPKPVA RKGQVDLKKS RLRMSLQEKL LTYYRNRAAI PAGEQARAKQ AAVDICAELR SFLRAKLPDM PLRDMYLSGS LYDDLQVVTA DHIQLIVPLV LEQNLWSCIP GEDTIMNVPG FFLVRRENPE YFPRGSSYWD RCVVGGYLSP KTVADTFEKV VAGSINWPAI G

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-280 of human MIEF1 (NP_061881.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SMCR7L

Target: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Andere Bezeichnung: MIEF1 (SMCR7L Produkte)

Hintergrund: Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.,MIEF1,HSU79252,MID51,SMCR7L,dJ1104E15.3,Cell Biology & Developmental Biology,MIEF1

Molekulargewicht: 8 kDa/15 kDa/51 kDa

Gen-ID: 54471

UniProt: Q9NQG6