MESDC2
Reaktivität: Human
WB, IHC, ELISA, ICC, IF
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
WB,1:500 - 1:2000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
MESDC2
(Mesoderm Development Candidate 2 (MESDC2))
Andere Bezeichnung
MESDC2
Hintergrund
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs. Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ formation by promoting cell-surface expression of LRP4 (By similarity. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE cells (By similarity.,MESDC2,BOCA,MESD,Cell Biology & Developmental Biology,Stem Cells,Mesenchymal Stem Cells,MESDC2