TNNI1 Antikörper

Produktnummer ABIN614371

Dieses Maus Monoklonal-Antikörper erkennt spezifisch TNNI1 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TNNI1 Antikörper (ABIN614371)

Target: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNNI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 12F10

Produktdetails anti-TNNI1 Antikörper

Spezifität: Recognizes Troponin I Skeletal (TNNI). Less than 0.05 % cross-reactivity with Cardiac TNI

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein A Chromatography.

Immunogen: Mouse Skeletal muscle Troponin I.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.4 with 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu TNNI1

Target: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Hintergrund: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium. This antibody reacts with subunit I of the troponin complex in human myocardium, where it is the only troponin I isotype present. It does not cross-react with troponin I of skeletal muscle cells.Synonyms: TNNI1

Gen-ID: 7135

NCBI Accession: NP_003272

UniProt: P19237