TNNI1 Antikörper (N-Term)

Produktnummer ABIN2777151

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-TNNI1 Antikörper wird verwendet zum Nachweis von TNNI1 in Proben von Human, Ratte, Maus, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB und IHC.

Kurzübersicht für TNNI1 Antikörper (N-Term) (ABIN2777151)

Target: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNNI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TNNI1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: TNNI1 Antibody - N-terminal region

Sequenz: MPEVERKPKI TASRKLLLKS LMLAKAKECW EQEHEEREAE KVRYLAERIP

Homologie: Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TNNI1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TNNI1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8111874

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TNNI1 Antikörper (ABIN2777151)

Salzler, Shah, Doré, Bauerlein, Miloscio, Latres, Papadopoulos, Olson, MacDonald, Duan: "Myostatin deficiency but not anti-myostatin blockade induces marked proteomic changes in mouse skeletal muscle." in: Proteomics, Vol. 16, Issue 14, pp. 2019-27, (2016) (PubMed).

Details zu TNNI1

Target: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Andere Bezeichnung: TNNI1

Hintergrund:

Background Information: Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Each troponin-tropomyosin complex contains 1 Molecule from each of the 3 troponins: T, C, and I. The troponin I (TNI) subfamily contains three genes: TNI-skeletal-fast-twitch, TNI-skeletal-slow-twitch, and TNI-cardiac. TNNI1 prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.

Gene Name: Troponin I type 1 (skeletal, slow)

Alternative Symbols: TNN1, SSTNI

Protein Name: Troponin I, slow skeletal muscle

Molekulargewicht: 21kDa

Gen-ID: 7135

NCBI Accession: NP_003272

UniProt: P19237