Caspase 7 Antikörper

Produktnummer ABIN614356

Produktdetails anti-Caspase 7 Antikörper

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reaktivität: Human, Maus, Ratte, Affe, Schwein, Hund, Kaninchen, Hamster, Schaf

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Caspase 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Detects an ~37 kDa protein, corresponding to the apparent molecular mass of the Caspase-7 on SDS-PAGE Immunoblots, in samples from Human, Mouse, Rat, Monkey, Dog, Sheep, Rabbit, Pig and Hamster origins. This antibody recognizes the unprocessed pro-caspase-7 (p35), caspase-7 lacking the short amino- terminal pro domain (32 kDa) and the fully processed Caspase-7 (p19) in apoptotic cell extracts.

Kreuzreaktivität (Details): Species reactivity (expected):Canine, Hamster, Monkey, Mouse, Porcine, Rabbit, Rat, Sheep.
Species reactivity (tested):Human.

Aufreinigung: Protein G Chromatography.

Immunogen: Recombinant Human CASP7.

Klon: 07-01-11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.4 mg/mL

Buffer: 10 mM Sodium Phosphate, pH 7.2, 50 mM Sodium Chloride with 0.1 mM PMSF

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Caspase 7

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Andere Bezeichnung: Caspase-7 (CASP7 Produkte)

Synonyme: xCaspase-7 antikoerper, caspase-7 antikoerper, caspase7 antikoerper, cmh-1 antikoerper, ice-lap3 antikoerper, mch3 antikoerper, CASP7 antikoerper, AI314680 antikoerper, CMH-1 antikoerper, ICE-IAP3 antikoerper, Mch3 antikoerper, mCASP-7 antikoerper, CASP-7 antikoerper, ICE-LAP3 antikoerper, LICE2 antikoerper, MCH3 antikoerper, Caspase-7 antikoerper, MCH3/SCA-2 antikoerper, SCA-2 antikoerper, caspase 7 antikoerper, caspase-7 antikoerper, caspase 7 S homeolog antikoerper, CASP7 antikoerper, xcaspase-7 antikoerper, casp7 antikoerper, casp7.S antikoerper, Casp7 antikoerper

Hintergrund: Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis, initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase 8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase 3 and Caspase 7, which in turn cause cell collapse.Synonyms: Apoptotic protease Mch-3, CASP-7, CASP7, CMH-1, ICE-like apoptotic protease 3, MCH3

Gen-ID: 840

NCBI Accession: NP_001218

UniProt: P55210

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity