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LIFR Antikörper (AA 500-700)

Der Rabbit Polyclonal Anti-LIFR-Antikörper wurde für WB validiert. Er ist geeignet, LIFR in Proben von Human zu detektieren.
Produktnummer ABIN6143204

Kurzübersicht für LIFR Antikörper (AA 500-700) (ABIN6143204)

Target

Alle LIFR Antikörper anzeigen
LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))

Reaktivität

  • 43
  • 18
  • 16
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 65
  • 7
Kaninchen

Klonalität

  • 66
  • 6
Polyklonal

Konjugat

  • 38
  • 18
  • 8
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser LIFR Antikörper ist unkonjugiert

Applikation

  • 58
  • 33
  • 24
  • 18
  • 17
  • 7
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 500-700

    Sequenz

    NPYTLYTFRI RCSTETFWKW SKWSNKKQHL TTEASPSKGP DTWREWSSDG KNLIIYWKPL PINEANGKIL SYNVSCSSDE ETQSLSEIPD PQHKAEIRLD KNDYIISVVA KNSVGSSPPS KIASMEIPND DLKIEQVVGM GKGILLTWHY DPNMTCDYVI KWCNSSRSEP CLMDWRKVPS NSTETVIESD EFRPGIRYNF F

    Kreuzreaktivität

    Maus

    Produktmerkmale

    Polyclonal Antibodies

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human LIFR (NP_002301.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))

    Andere Bezeichnung

    LIFR

    Hintergrund

    This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5,8)(p13,q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.,LIFR,CD118,LIF-R,SJS2,STWS,SWS,Cell Biology & Developmental Biology,Immunology & Inflammation,CD markers,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,Stem Cells,Embryonic Stem Cells,LIFR

    Molekulargewicht

    123 kDa

    Gen-ID

    3977

    UniProt

    P42702

    Pathways

    JAK-STAT Signalweg, Growth Factor Binding
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