Kallikrein 6 Antikörper (C-Term)

Produktnummer ABIN6142958

Der Kaninchen Polyklonal Anti-Kallikrein 6-Antikörper wurde für WB validiert. Er ist geeignet, Kallikrein 6 in Proben von Human zu detektieren.

Kurzübersicht für Kallikrein 6 Antikörper (C-Term) (ABIN6142958)

Target: Kallikrein 6 (KLK6)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Kallikrein 6 Antikörper

Bindungsspezifität: C-Term

Sequenz: AASHDQDIML LRLARPAKLS ELIQPLPLER DCSANTTSCH ILGWGKTADG DFPDTIQCAY IHLVSREECE HAYPGQITQN MLCAGDEKYG KDSCQGDSGG PLVCGDHLRG LVSWGNIPCG SKEKPGVYTN VCRYTNWIQK TIQAK

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human KLK6 (NP_002765.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Kallikrein 6

Target: Kallikrein 6 (KLK6)

Andere Bezeichnung: KLK6

Hintergrund: This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer's and Parkinson's disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,KLK6,Bssp,Klk7,PRSS18,PRSS9,SP59,hK6,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Ubiquitin,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,KLK6

Molekulargewicht: 4 kDa/15 kDa/26 kDa

Gen-ID: 5653

UniProt: Q92876

Pathways: Komplementsystem, Regulation of G-Protein Coupled Receptor Protein Signaling