ISL1 Antikörper (AA 1-349)

Produktnummer ABIN6142549

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ISL1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ISL1 Antikörper (AA 1-349) (ABIN6142549)

Target: ISL1 (ISL LIM Homeobox 1 (ISL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ISL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ISL1 Antikörper

Bindungsspezifität: AA 1-349

Sequenz: MGDMGDPPKK KRLISLCVGC GNQIHDQYIL RVSPDLEWHA ACLKCAECNQ YLDESCTCFV RDGKTYCKRD YIRLYGIKCA KCSIGFSKND FVMRARSKVY HIECFRCVAC SRQLIPGDEF ALREDGLFCR ADHDVVERAS LGAGDPLSPL HPARPLQMAA EPISARQPAL RPHVHKQPEK TTRVRTVLNE KQLHTLRTCY AANPRPDALM KEQLVEMTGL SPRVIRVWFQ NKRCKDKKRS IMMKQLQQQQ PNDKTNIQGM TGTPMVAASP ERHDGGLQAN PVEVQSYQPP WKVLSDFALQ SDIDQPAFQQ LVNFSEGGPG SNSTGSEVAS MSSQLPDTPN SMVASPIEA

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-349 of human Islet1 (NP_002193.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ISL1

Target: ISL1 (ISL LIM Homeobox 1 (ISL1))

Andere Bezeichnung: ISL1

Hintergrund: This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.,ISL1,ISLET1,Isl-1,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cells,Cardiovascular,Heart,Cardiogenesis,Neuron marker,ISL1

Molekulargewicht: 39 kDa

Gen-ID: 3670

UniProt: P61371

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding