Metabotropic Glutamate Receptor 5 Antikörper (AA 870-1070)

Produktnummer ABIN6141427

Der Kaninchen Polyklonal Anti-Metabotropic Glutamate Receptor 5-Antikörper wurde für WB validiert. Er ist geeignet, Metabotropic Glutamate Receptor 5 in Proben von Human zu detektieren.

Kurzübersicht für Metabotropic Glutamate Receptor 5 Antikörper (AA 870-1070) (ABIN6141427)

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Metabotropic Glutamate Receptor 5 Antikörper

Bindungsspezifität: AA 870-1070

Sequenz: GSSGETLRYK DRRLAQHKSE IECFTPKGSM GNGGRATMSS SNGKSVTWAQ NEKSSRGQHL WQRLSIHINK KENPNQTAVI KPFPKSTESR GLGAGAGAGG SAGGVGATGG AGCAGAGPGG PESPDAGPKA LYDVAEAEEH FPAPARPRSP SPISTLSHRA GSASRTDDDV PSLHSEPVAR SSSSQGSLME QISSVVTRFT A

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 870-1070 of human GRM5 (NP_001137303.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Metabotropic Glutamate Receptor 5

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Andere Bezeichnung: GRM5

Hintergrund: This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.,GRM5,GPRC1E,MGLUR5,PPP1R86,mGlu5,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,GRM5

Molekulargewicht: 105 kDa/128 kDa/132 kDa

Gen-ID: 2915

UniProt: P41594

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity