GRIA4 Antikörper (AA 254-433)

Produktnummer ABIN6141388

Produktdetails anti-GRIA4 Antikörper

Target: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Bindungsspezifität: AA 254-433

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HGGANVTGFQ LVDFNTPMVI KLMDRWKKLD QREYPGSETP PKYTSALTYD GVLVMAETFR SLRRQKIDIS RRGNAGDCLA NPAAPWGQGI DMERTLKQVR IQGLTGNVQF DHYGRRVNYT MDVFELKSTG PRKVGYWNDM DKLVLIQDVP TLGNDTAAIE NRTVVVTTIM PLMKNPILRN

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 254-433 of human GluR4/GluA4/GluR4/GluA4/GRIA4 (NP_001070712.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:4000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GRIA4

Target: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Andere Bezeichnung: GRIA4 (GRIA4 Produkte)

Synonyme: GLUR4 antikoerper, GLUR4C antikoerper, GLURD antikoerper, GluA4 antikoerper, GluR4 antikoerper, GluR4d antikoerper, GLUR4/D antikoerper, glur4 antikoerper, GluR-D antikoerper, Glur-4 antikoerper, Glur4 antikoerper, Gluralpha4 antikoerper, spkw1 antikoerper, DKFZp459P0616 antikoerper, glur4a antikoerper, gria4 antikoerper, iGluR4 antikoerper, ZfGluR4b antikoerper, fj46g06 antikoerper, glur4b antikoerper, wu:fj46g06 antikoerper, glutamate ionotropic receptor AMPA type subunit 4 antikoerper, glutamate receptor, ionotropic, AMPA 4 antikoerper, glutamate receptor, ionotropic, AMPA4 (alpha 4) antikoerper, glutamate receptor, ionotropic, AMPA 4a antikoerper, glutamate receptor, ionotropic, AMPA 4b antikoerper, GRIA4 antikoerper, gria4 antikoerper, Gria4 antikoerper, gria4a antikoerper, gria4b antikoerper

Hintergrund: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.,GRIA4,GLUR4,GLUR4C,GLURD,GluA4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Dopamine Signaling in Parkinson's Disease,GRIA4

Molekulargewicht: 49 kDa/100 kDa

Gen-ID: 2893

UniProt: P48058

Pathways: PI3K-Akt Signalweg