Glypican 3 Antikörper (AA 290-550)

Produktnummer ABIN6141306

Der Kaninchen Polyklonal Anti-Glypican 3-Antikörper wurde für IF und WB validiert. Er ist geeignet, Glypican 3 in Proben von Human zu detektieren.

Kurzübersicht für Glypican 3 Antikörper (AA 290-550) (ABIN6141306)

Target: Glypican 3 (GPC3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glypican 3 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Western Blotting (WB)

Produktdetails anti-Glypican 3 Antikörper

Bindungsspezifität: AA 290-550

Sequenz: VEIDKYWREY ILSLEELVNG MYRIYDMENV LLGLFSTIHD SIQYVQKNAG KLTTTIGKLC AHSQQRQYRS AYYPEDLFID KKVLKVAHVE HEETLSSRRR ELIQKLKSFI SFYSALPGYI CSHSPVAEND TLCWNGQELV ERYSQKAARN GMKNQFNLHE LKMKGPEPVV SQIIDKLKHI NQLLRTMSMP KGRVLDKNLD EEGFESGDCG DDEDECIGGS GDGMIKVKNQ LRFLAELAYD LDVDDAPGNS QQATPKDNEI S

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 290-550 of human Glypican 3 (GPC3) (GPC3) (NP_004475.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Glypican 3

Target: Glypican 3 (GPC3)

Andere Bezeichnung: GPC3

Hintergrund: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.,GPC3,DGSX,GTR2-2,MXR7,OCI-5,SDYS,SGB,SGBS,SGBS1,glypican-3,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Stem Cells,GPC3

Molekulargewicht: 59 kDa/65 kDa/68 kDa

Gen-ID: 2719

UniProt: P51654

Pathways: Glycosaminoglycan Metabolic Process