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GEN1 Antikörper (AA 669-908)

Der Kaninchen Polyklonal Anti-GEN1-Antikörper wurde für WB validiert. Er ist geeignet, GEN1 in Proben von Human zu detektieren.
Produktnummer ABIN6141058

Kurzübersicht für GEN1 Antikörper (AA 669-908) (ABIN6141058)

Target

Alle GEN1 Antikörper anzeigen
GEN1 (Gen Endonuclease Homolog 1 (GEN1))

Reaktivität

  • 25
  • 9
Human

Wirt

  • 25
Kaninchen

Klonalität

  • 25
Polyklonal

Konjugat

  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GEN1 Antikörper ist unkonjugiert

Applikation

  • 25
  • 13
  • 13
  • 10
  • 3
  • 3
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 8
    • 2
    • 1
    AA 669-908

    Sequenz

    LQDLPLKERI FTKLSYPQDN LQPDVNLKTL SILSVKESCI ANSGSDCTSH LSKDLPGIPL QNESRDSKIL KGDQLLQEDY KVNTSVPYSV SNTVVKTCNV RPPNTALDHS RKVDMQTTRK ILMKKSVCLD RHSSDEQSAP VFGKAKYTTQ RMKHSSQKHN SSHFKESGHN KLSSPKIHIK ETEQCVRSYE TAENEESCFP DSTKSSLSSL QCHKKENNSG TCLDSPLPLR QRLKLRFQST

    Kreuzreaktivität

    Human, Maus

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 669-908 of human GEN1 (NP_872431.3).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000

    Kommentare

    HIGH QUALITY

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    GEN1 (Gen Endonuclease Homolog 1 (GEN1))

    Andere Bezeichnung

    GEN1

    Hintergrund

    This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants.,GEN1,Gen,Epigenetics & Nuclear Signaling,DNA Damage & Repair,GEN1

    Molekulargewicht

    102 kDa

    Gen-ID

    348654

    UniProt

    Q17RS7

    Pathways

    DNA Reparatur
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