GEN1 Antikörper (AA 669-908)

Produktnummer ABIN6141058

Der Kaninchen Polyklonal Anti-GEN1-Antikörper wurde für WB validiert. Er ist geeignet, GEN1 in Proben von Human zu detektieren.

Kurzübersicht für GEN1 Antikörper (AA 669-908) (ABIN6141058)

Target: GEN1 (Gen Endonuclease Homolog 1 (GEN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GEN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GEN1 Antikörper

Bindungsspezifität: AA 669-908

Sequenz: LQDLPLKERI FTKLSYPQDN LQPDVNLKTL SILSVKESCI ANSGSDCTSH LSKDLPGIPL QNESRDSKIL KGDQLLQEDY KVNTSVPYSV SNTVVKTCNV RPPNTALDHS RKVDMQTTRK ILMKKSVCLD RHSSDEQSAP VFGKAKYTTQ RMKHSSQKHN SSHFKESGHN KLSSPKIHIK ETEQCVRSYE TAENEESCFP DSTKSSLSSL QCHKKENNSG TCLDSPLPLR QRLKLRFQST

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 669-908 of human GEN1 (NP_872431.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GEN1

Target: GEN1 (Gen Endonuclease Homolog 1 (GEN1))

Andere Bezeichnung: GEN1

Hintergrund: This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants.,GEN1,Gen,Epigenetics & Nuclear Signaling,DNA Damage & Repair,GEN1

Molekulargewicht: 102 kDa

Gen-ID: 348654

UniProt: Q17RS7

Pathways: DNA Reparatur