FOXO3 Antikörper (AA 394-672)

Produktnummer ABIN6140755

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FOXO3 in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Maus und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für FOXO3 Antikörper (AA 394-672) (ABIN6140755)

Target: FOXO3 (Forkhead Box O3 (FOXO3))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXO3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-FOXO3 Antikörper

Bindungsspezifität: AA 394-672

Sequenz: ALPPSQPSPP GGLMQRGSSF PYTAKSSGLG SPTGSFNSTV FGPSSLNSLR QSPMQTIQEN RPATFSSVSH YGNQTLQDLL ASDSLSHSDV MMTQSDPLMS QASTAVSAQN ARRNVMLRND PMMSFAAQPT QGSLVNQNLL HHQHQTQGAL GGSRALSNSV SNMGLSDSSS LGSAKHQQQS PASQSMQTLS DSLSGSSLYS ASANLPVMGH DKFPSDLDLD MFNGSLECDM ESIIRSELMD ADGLDFNFDS LISTQNVVGL NVGNFTGAKQ ASSQSWVPG

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 394-672 of mouse FOXO3A (NP_062714.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-FOXO3 Antikörper (ABIN6140755)

Li, Chan, Yu, Bei, Chen, Zhou, Cheng, Chen, Ziegler, Rowe, Das, Xiao: "miR-29b contributes to multiple types of muscle atrophy." in: Nature communications, Vol. 8, pp. 15201, (2018) (PubMed).

Liu, Cai, Hu, Mei, Zhang, Ouyang, Wang, Zhang, Xiao: "Forkhead Transcription Factor 3a (FOXO3a) Modulates Hypoxia Signaling via Up-regulation of the von Hippel-Lindau Gene (VHL)." in: The Journal of biological chemistry, Vol. 291, Issue 49, pp. 25692-25705, (2017) (PubMed).

Yang, Wang, Xiong, Kong, Qiu, Shen, Huang: "Activation of SIRT3 attenuates triptolide-induced toxicity through closing mitochondrial permeability transition pore in cardiomyocytes." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 34, pp. 128-137, (2017) (PubMed).

Details zu FOXO3

Target: FOXO3 (Forkhead Box O3 (FOXO3))

Andere Bezeichnung: FOXO3

Hintergrund: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.,FOXO3,AF6q21,FKHRL1,FKHRL1P2,FOXO2,FOXO3A,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Cell Cycle,G1/S Checkpoint,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,FOXO3

Molekulargewicht: 71 kDa

Gen-ID: 56484

UniProt: Q9WVH4

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis