EPH Receptor B2 Antikörper (AA 250-540)
Kurzübersicht für EPH Receptor B2 Antikörper (AA 250-540) (ABIN6140223)
Target
Alle EPH Receptor B2 (EPHB2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 250-540
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Sequenz
- PIGRCMCKAG FEAVENGTVC RGCPSGTFKA NQGDEACTHC PINSRTTSEG ATNCVCRNGY YRADLDPLDM PCTTIPSAPQ AVISSVNETS LMLEWTPPRD SGGREDLVYN IICKSCGSGR GACTRCGDNV QYAPRQLGLT EPRIYISDLL AHTQYTFEIQ AVNGVTDQSP FSPQFASVNI TTNQAAPSAV SIMHQVSRTV DSITLSWSQP DQPNGVILDY ELQYYEKELS EYNATAIKSP TNTVTVQGLK AGAIYVFQVR ARTVAGYGRY SGKMYFQTMT EAEYQTSIQE K
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 250-540 of human EPHB2 (NP_059145.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- EPH Receptor B2 (EPHB2)
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Andere Bezeichnung
- EPHB2
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Hintergrund
- This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.,EPHB2,CAPB,DRT,EK5,EPHT3,ERK,Hek5,PCBC,Tyro5,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Neuroscience,Cell Type Marker,Cardiovascular,Angiogenesis,Neuron marker,Growth Cone,EPHB2
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Molekulargewicht
- 109 kDa/110 kDa/117 kDa
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Gen-ID
- 2048
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UniProt
- P29323
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Pathways
- RTK Signalweg, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine
Target
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