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Endothelin 3 Antikörper (AA 17-187)

This anti-Endothelin 3 antibody (ABIN6139934) is a Rabbit Polyclonal antibody detecting Endothelin 3 in WB. Suitable for Human.
Produktnummer ABIN6139934

Kurzübersicht für Endothelin 3 Antikörper (AA 17-187) (ABIN6139934)

Target

Alle Endothelin 3 (EDN3) Antikörper anzeigen
Endothelin 3 (EDN3)

Reaktivität

  • 32
  • 6
  • 4
  • 2
  • 2
  • 1
Human

Wirt

  • 33
  • 3
Kaninchen

Klonalität

  • 34
  • 2
Polyklonal

Konjugat

  • 24
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Endothelin 3 Antikörper ist unkonjugiert

Applikation

  • 24
  • 13
  • 8
  • 5
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 17-187

    Sequenz

    AGFVPCSQSG DAGRRGVSQA PTAARSEGDC EETVAGPGEE TVAGPGEGTV APTALQGPSP GSPGQEQAAE GAPEHHRSRR CTCFTYKDKE CVYYCHLDII WINTPEQTVP YGLSNYRGSF RGKRSAGPLP GNLQLSHRPH LRCACVGRYD KACLHFCTQT LDVSSNSRTA E

    Kreuzreaktivität

    Human

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 17-187 of human EDN3 (NP_996917.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Endothelin 3 (EDN3)

    Andere Bezeichnung

    EDN3

    Hintergrund

    The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.,EDN3,ET-3,ET3,HSCR4,PPET3,WS4B,Cancer,Invasion and Metastasis,Signal Transduction,Neuroscience,EDN3

    Molekulargewicht

    23 kDa/25 kDa

    Gen-ID

    1908

    UniProt

    P14138

    Pathways

    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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