DUOX1 Antikörper (AA 1312-1551)

Produktnummer ABIN6139857

Der Kaninchen Polyklonal Anti-DUOX1-Antikörper wurde für WB validiert. Er ist geeignet, DUOX1 in Proben von Human zu detektieren.

Kurzübersicht für DUOX1 Antikörper (AA 1312-1551) (ABIN6139857)

Target: DUOX1 (Dual Oxidase 1 (DUOX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUOX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DUOX1 Antikörper

Bindungsspezifität: AA 1312-1551

Sequenz: ALGTTEYHPF TLTSAPHEDT LSLHIRAAGP WTTRLREIYS APTGDRCARY PKLYLDGPFG EGHQEWHKFE VSVLVGGGIG VTPFASILKD LVFKSSVSCQ VFCKKIYFIW VTRTQRQFEW LADIIREVEE NDHQDLVSVH IYITQLAEKF DLRTTMLYIC ERHFQKVLNR SLFTGLRSIT HFGRPPFEPF FNSLQEVHPQ VRKIGVFSCG PPGMTKNVEK ACQLINRQDR THFSHHYENF

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1312-1551 of human DUOX1 (NP_059130.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DUOX1

Target: DUOX1 (Dual Oxidase 1 (DUOX1))

Andere Bezeichnung: DUOX1

Hintergrund: The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.,DUOX1,LNOX1,NOXEF1,THOX1,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,DUOX1

Molekulargewicht: 137 kDa/177 kDa

Gen-ID: 53905

UniProt: Q9NRD9