Desmocollin 1 Antikörper (AA 480-690)

Produktnummer ABIN6139825

Der Kaninchen Polyklonal Anti-Desmocollin 1-Antikörper wurde für WB validiert. Er ist geeignet, Desmocollin 1 in Proben von Human zu detektieren.

Kurzübersicht für Desmocollin 1 Antikörper (AA 480-690) (ABIN6139825)

Target: Desmocollin 1 (DSC1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmocollin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Desmocollin 1 Antikörper

Bindungsspezifität: AA 480-690

Sequenz: SQDGFPAGQE LLGYKALDPE ISSGEGLRYQ KLGDEDNWFE INQHTGDLRT LKVLDRESKF VKNNQYNISV VAVDAVGRSC TGTLVVHLDD YNDHAPQIDK EVTICQNNED FAVLKPVDPD GPENGPPFQF FLDNSASKNW NIEEKDGKTA ILRQRQNLDY NYYSVPIQIK DRHGLVATHM LTVRVCDCST PSECRMKDKS TRDVRPNVIL G

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 480-690 of human DSC1 (NP_077739.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Desmocollin 1

Target: Desmocollin 1 (DSC1)

Andere Bezeichnung: DSC1

Hintergrund: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein.,DSC1,CDHF1,DG2/DG3,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Cytoskeleton,Extracellular Matrix,DSC1

Molekulargewicht: 93 kDa/99 kDa

Gen-ID: 1823

UniProt: Q08554