TdT Antikörper (AA 260-509)
Kurzübersicht für TdT Antikörper (AA 260-509) (ABIN6139759)
Target
Alle TdT (DNTT) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 260-509
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Sequenz
- LKTSEKWFRM GFRTLSKVRS DKSLKFTRMQ KAGFLYYEDL VSCVTRAEAE AVSVLVKEAV WAFLPDAFVT MTGGFRRGKK MGHDVDFLIT SPGSTEDEEQ LLQKVMNLWE KKGLLLYYDL VESTFEKLRL PSRKVDALDH FQKCFLIFKL PRQRVDSDQS SWQEGKTWKA IRVDLVLCPY ERRAFALLGW TGSRQFERDL RRYATHERKM ILDNHALYDK TKRIFLKAES EEEIFAHLGL DYIEPWERNA
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 260-509 of human DNTT (NP_004079.3).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
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Andere Bezeichnung
- DNTT
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Hintergrund
- This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.,DNTT,TDT,Immunology & Inflammation,DNTT
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Molekulargewicht
- 58 kDa
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Gen-ID
- 1791
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UniProt
- P04053
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Pathways
- DNA Reparatur
Target
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