CXCR3 Antikörper (AA 289-368)

Produktnummer ABIN6139279

Produktdetails anti-CXCR3 Antikörper

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Bindungsspezifität: AA 289-368

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NCGRESRVDV AKSVTSGLGY MHCCLNPLLY AFVGVKFRER MWMLLLRLGC PNQRGLQRQP SSSRRDSSWS ETSEASYSGL

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 289-368 of human CXCR3 (NP_001495.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CXCR3

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Andere Bezeichnung: CXCR3 (CXCR3 Produkte)

Synonyme: CD182 antikoerper, CD183 antikoerper, CKR-L2 antikoerper, CMKAR3 antikoerper, GPR9 antikoerper, IP10-R antikoerper, Mig-R antikoerper, MigR antikoerper, Cd183 antikoerper, Cmkar3 antikoerper, CXCR3 antikoerper, cxcr3 antikoerper, Gpr9 antikoerper, CXC-R3 antikoerper, CXCR-3 antikoerper, zgc:92301 antikoerper, sb:eu378 antikoerper, C-X-C motif chemokine receptor 3 antikoerper, chemokine (C-X-C motif) receptor 3 antikoerper, chemokine (C-X-C motif) receptor 3, tandem duplicate 2 antikoerper, chemokine (C-X-C motif) receptor 3, tandem duplicate 1 antikoerper, CXCR3 antikoerper, Cxcr3 antikoerper, cxcr3 antikoerper, cxcr3.2 antikoerper, cxcr3.1 antikoerper

Hintergrund: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).,CXCR3,CD182,CD183,CKR-L2,CMKAR3,GPR9,IP10-R,Mig-R,MigR,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,Chemokines,Chemokine,Neuroscience,Calcium Signaling,Cardiovascular,CXCR3

Molekulargewicht: 28 kDa/40 kDa/45 kDa

Gen-ID: 2833

UniProt: P49682