CXCR3 Antikörper
Kurzübersicht für CXCR3 Antikörper (ABIN7266318)
Target
Alle CXCR3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- CXCR3 Rabbit mAb
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human CXCR3
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
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Andere Bezeichnung
- CXCR3
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Hintergrund
- This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011],CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR,Calcium Signaling,Cardiovascular,CDs,Cell Intrinsic Innate Immunity Signaling Pathway,G protein signaling,G protein signaling_G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,Innate Immunity_Chemokines,Neuroscience,Signal Transduction,CXCR3
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Molekulargewicht
- 41kDa
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Gen-ID
- 2833
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UniProt
- P49682
Target
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