Cathepsin D Antikörper (AA 65-412)

Produktnummer ABIN6139223

Dieses Anti-Cathepsin D-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cathepsin D in WB und IHC. Geeignet für Human.

Kurzübersicht für Cathepsin D Antikörper (AA 65-412) (ABIN6139223)

Target: Cathepsin D (CTSD)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Cathepsin D Antikörper

Bindungsspezifität: AA 65-412

Sequenz: GPIPEVLKNY MDAQYYGEIG IGTPPQCFTV VFDTGSSNLW VPSIHCKLLD IACWIHHKYN SDKSSTYVKN GTSFDIHYGS GSLSGYLSQD TVSVPCQSAS SASALGGVKV ERQVFGEATK QPGITFIAAK FDGILGMAYP RISVNNVLPV FDNLMQQKLV DQNIFSFYLS RDPDAQPGGE LMLGGTDSKY YKGSLSYLNV TRKAYWQVHL DQVEVASGLT LCKEGCEAIV DTGTSLMVGP VDEVRELQKA IGAVPLIQGE YMIPCEKVST LPAITLKLGG KGYKLSPEDY TLKVSQAGKT LCLSGFMGMD IPPPSGPLWI LGDVFIGRYY TVFDRDNNRV GFAEAARL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 65-412 of human Cathepsin D (NP_001900.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Cathepsin D

Target: Cathepsin D (CTSD)

Andere Bezeichnung: CTSD

Hintergrund: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.,CLN10,CPSD,HEL-S-130P,Cathepsin D,CTSD,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Ubiquitin,Neuroscience,CTSD

Molekulargewicht: 44 kDa

Gen-ID: 1509

UniProt: P07339

Pathways: Peptide Hormone Metabolism