CHMP4B Antikörper (AA 1-224)

Produktnummer ABIN6138549

Dieses Anti-CHMP4B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CHMP4B in WB und IF. Geeignet für Human.

Kurzübersicht für CHMP4B Antikörper (AA 1-224) (ABIN6138549)

Target: CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHMP4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-CHMP4B Antikörper

Bindungsspezifität: AA 1-224

Sequenz: MSVFGKLFGA GGGKAGKGGP TPQEAIQRLR DTEEMLSKKQ EFLEKKIEQE LTAAKKHGTK NKRAALQALK RKKRYEKQLA QIDGTLSTIE FQREALENAN TNTEVLKNMG YAAKAMKAAH DNMDIDKVDE LMQDIADQQE LAEEISTAIS KPVGFGEEFD EDELMAELEE LEQEELDKNL LEISGPETVP LPNVPSIALP SKPAKKKEEE DDDMKELENW AGSM

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human CHMP4B (NP_789782.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CHMP4B

Target: CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

Andere Bezeichnung: CHMP4B

Hintergrund: This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.,CHMP4B,C20orf178,CHMP4A,CTPP3,CTRCT31,SNF7,SNF7-2,Shax1,VPS32B,Vps32-2,dJ553F4.4,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Cell Cycle,Immunology & Inflammation,Cytokines,Regulators,CHMP4B

Molekulargewicht: 24 kDa

Gen-ID: 128866

UniProt: Q9H444