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CHMP4B Antikörper (Middle Region)

CHMP4B Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2785348
  • Target Alle CHMP4B Antikörper anzeigen
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    Middle Region
    Reaktivität
    • 44
    • 21
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 43
    • 1
    Kaninchen
    Klonalität
    • 43
    • 1
    Polyklonal
    Konjugat
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CHMP4B Antikörper ist unkonjugiert
    Applikation
    • 19
    • 19
    • 18
    • 13
    • 13
    • 12
    • 5
    • 3
    • 3
    • 3
    Western Blotting (WB)
    Sequenz
    EEISTAISKP VGFGEEFDED ELMAELEELE QEELDKNLLE ISGPETVPLP
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CHMP4B. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human CHMP4B
    Top Product
    Discover our top product CHMP4B Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 224 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bodon, Chassefeyre, Pernet-Gallay, Martinelli, Effantin, Hulsik, Belly, Goldberg, Chatellard-Causse, Blot, Schoehn, Weissenhorn, Sadoul: "Charged multivesicular body protein 2B (CHMP2B) of the endosomal sorting complex required for transport-III (ESCRT-III) polymerizes into helical structures deforming the plasma membrane." in: The Journal of biological chemistry, Vol. 286, Issue 46, pp. 40276-86, (2011) (PubMed).

  • Target
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    Andere Bezeichnung
    CHMP4B (CHMP4B Produkte)
    Synonyme
    C20orf178 antikoerper, CHMP4A antikoerper, CTPP3 antikoerper, CTRCT31 antikoerper, SNF7 antikoerper, SNF7-2 antikoerper, Shax1 antikoerper, VPS32B antikoerper, Vps32-2 antikoerper, dJ553F4.4 antikoerper, 2010012F05Rik antikoerper, C76846 antikoerper, Snf7-2 antikoerper, RGD1309846 antikoerper, RGD1565889 antikoerper, CHMP4b antikoerper, chmp4b antikoerper, chmp4b.S antikoerper, CHMP4c antikoerper, c20orf178 antikoerper, wu:fc96b02 antikoerper, zgc:55566 antikoerper, charged multivesicular body protein 4B antikoerper, charged multivesicular body protein 4Ba antikoerper, charged multivesicular body protein 4B L homeolog antikoerper, charged multivesicular body protein 4Bb antikoerper, CHMP4B antikoerper, Chmp4b antikoerper, chmp4ba antikoerper, chmp4b.L antikoerper, chmp4bb antikoerper
    Hintergrund
    This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.
    Alias Symbols: C20orf178, CHMP4A, CTPP3, SNF7, SNF7-2, Shax1, dJ553F4.4, VPS32B, Vps32-2
    Protein Interaction Partner: UBC, TP53, CHMP6, UBE2I, PDCD6IP, VCAM1, ITGA4, RPLP0P6, MVP, ATP6V1B1, BROX, CHMP4B, CHMP4C, CHMP1B, CHMP3, CHMP5, CHMP4A, HIPK2, VPS4A, STAMBP, PIAS2, EXOSC9, HCVgp1, NOLC1, PTPN23,
    Protein Size: 224
    Molekulargewicht
    25 kDa
    Gen-ID
    128866
    NCBI Accession
    NM_176812, NP_789782
    UniProt
    Q9H444
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