Cadherin 5 Antikörper (AA 650-750)
Kurzübersicht für Cadherin 5 Antikörper (AA 650-750) (ABIN6138297)
Target
Alle Cadherin 5 (CDH5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 650-750
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Sequenz
- GGEMDTTSYD VSVLNSVRRG GAKPPRPALD ARPSLYAQVQ KPPRHAPGAH GGPGEMAAMI EVKKDEADHD GDGPPYDTLH IYGYEGSESI AESLSSLGTD S
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 650-750 of human CDH5 (NP_001786.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cadherin 5 (CDH5)
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Andere Bezeichnung
- CDH5
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Hintergrund
- This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.,CDH5,7B4,CD144,cadherin-5,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Cell Adhesion Molecules,Tight Junctions,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Cardiovascular,Cardiovascular Markers,Endothelial Cells,CDH5
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Molekulargewicht
- 74 kDa/87 kDa
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Gen-ID
- 1003
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UniProt
- P33151
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Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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