CD38 Antikörper (AA 46-300)

Produktnummer ABIN6138177

Dieses Anti-CD38-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD38 in IHC, WB und IF. Geeignet für Human.

Kurzübersicht für CD38 Antikörper (AA 46-300) (ABIN6138177)

Target: CD38

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD38 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-CD38 Antikörper

Bindungsspezifität: AA 46-300

Sequenz: WRQQWSGPGT TKRFPETVLA RCVKYTEIHP EMRHVDCQSV WDAFKGAFIS KHPCNITEED YQPLMKLGTQ TVPCNKILLW SRIKDLAHQF TQVQRDMFTL EDTLLGYLAD DLTWCGEFNT SKINYQSCPD WRKDCSNNPV SVFWKTVSRR FAEAACDVVH VMLNGSRSKI FDKNSTFGSV EVHNLQPEKV QTLEAWVIHG GREDSRDLCQ DPTIKELESI ISKRNIQFSC KNIYRPDKFL QCVKNPEDSS CTSEI

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 46-300 of human CD38 (NP_001766.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CD38

Target: CD38

Hintergrund: The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.,CD38,ADPRC 1,ADPRC1,Cancer,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CD38

Molekulargewicht: 13 kDa/34 kDa

Gen-ID: 952

UniProt: P28907