CCR8 Antikörper (AA 296-355)

Produktnummer ABIN6138101

Dieses Anti-CCR8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CCR8 in WB. Geeignet für Human.

Kurzübersicht für CCR8 Antikörper (AA 296-355) (ABIN6138101)

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CCR8 Antikörper

Bindungsspezifität: AA 296-355

Sequenz: NPVIYAFVGE KFKKHLSEIF QKSCSQIFNY LGRQMPRESC EKSSSCQQHS SRSSSVDYIL

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 296-355 of human CCR8 (NP_005192.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Andere Bezeichnung: CCR8

Hintergrund: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.,CCR8,CC-CKR-8,CCR-8,CDw198,CKRL1,CMKBR8,CMKBRL2,CY6,GPRCY6,TER1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,Chemokines,Chemokine,CCR8

Molekulargewicht: 31 kDa/40 kDa

Gen-ID: 1237

UniProt: P51685