Caspase 2 Antikörper (AA 153-452)
Kurzübersicht für Caspase 2 Antikörper (AA 153-452) (ABIN6137960)
Target
Alle Caspase 2 (CASP2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 153-452
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Sequenz
- KLRLSTDTVE HSLDNKDGPV CLQVKPCTPE FYQTHFQLAY RLQSRPRGLA LVLSNVHFTG EKELEFRSGG DVDHSTLVTL FKLLGYDVHV LCDQTAQEMQ EKLQNFAQLP AHRVTDSCIV ALLSHGVEGA IYGVDGKLLQ LQEVFQLFDN ANCPSLQNKP KMFFIQACRG DETDRGVDQQ DGKNHAGSPG CEESDAGKEK LPKMRLPTRS DMICGYACLK GTAAMRNTKR GSWYIEALAQ VFSERACDMH VADMLVKVNA LIKDREGYAP GTEFHRCKEM SEYCSTLCRH LYLFPGHPPT
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 153-452 of human Caspase-2 (NP_116764.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
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Andere Bezeichnung
- CASP2
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Hintergrund
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,CASP2,CASP-2,ICH1,NEDD-2,NEDD2,PPP1R57,caspase-2,Cancer,Invasion and Metastasis,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Mitochondrial Control of Apoptosis,Ubiquitin,Endocrine & Metabolism,Immunology & Inflammation,CASP2
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Molekulargewicht
- 10 kDa/34 kDa/50 kDa
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Gen-ID
- 835
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UniProt
- P42575
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Neurotrophin Signalübertragung
Target
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