Calpain S1 Antikörper (AA 69-268)

Produktnummer ABIN6137928

Produktdetails anti-Calpain S1 Antikörper

Target: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Bindungsspezifität: AA 69-268

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calpain S1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: ISEAAAQYNP EPPPPRTHYS NIEANESEEV RQFRRLFAQL AGDDMEVSAT ELMNILNKVV TRHPDLKTDG FGIDTCRSMV AVMDSDTTGK LGFEEFKYLW NNIKRWQAIY KQFDTDRSGT ICSSELPGAF EAAGFHLNEH LYNMIIRRYS DESGNMDFDN FISCLVRLDA MFRAFKSLDK DGTGQIQVNI QEWLQLTMYS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 69-268 of human Calpain small subunit 1 (NP_001740.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-Calpain S1 Antikörper (ABIN6137928)

Liu, Lou, Li, Xu, Ruan, Xiao, Qiu, Bao, Yuan, Huang, Wang, Cao, Chen, Yang, Zhang: "Calpain and AR-V7: Two potential therapeutic targets to overcome acquired docetaxel resistance in castration-resistant prostate cancer cells." in: Oncology reports, Vol. 37, Issue 6, pp. 3651-3659, (2018) (PubMed).

Details zu Calpain S1

Target: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Andere Bezeichnung: CAPNS1 (CAPNS1 Produkte)

Synonyme: 30K antikoerper, CALPAIN4 antikoerper, CANP antikoerper, CANPS antikoerper, CAPN4 antikoerper, CDPS antikoerper, CSS1 antikoerper, Capn4 antikoerper, CAPNS1 antikoerper, Capa-4 antikoerper, Capa4 antikoerper, D7Ertd146e antikoerper, MGC84330 antikoerper, capns1 antikoerper, cb616 antikoerper, wu:fb81g08 antikoerper, wu:fl09e04 antikoerper, zgc:110603 antikoerper, calpain small subunit 1 antikoerper, calpain, small subunit 1 antikoerper, calpain, small subunit 1 L homeolog antikoerper, calpain, small subunit 1 a antikoerper, CAPNS1 antikoerper, Capns1 antikoerper, capns1.L antikoerper, capns1a antikoerper

Hintergrund: This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.,CAPNS1,CALPAIN4,CANP,CANPS,CAPN4,CDPS,CSS1,Signal Transduction,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,CAPNS1

Molekulargewicht: 28 kDa

Gen-ID: 826

UniProt: P04632

Pathways: Apoptose