Caldesmon Antikörper (AA 1-240)
Kurzübersicht für Caldesmon Antikörper (AA 1-240) (ABIN6137866)
Target
Alle Caldesmon (CALD1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1-240
-
Sequenz
- MDDFERRREL RRQKREEMRL EAERIAYQRN DDDEEEAARE RRRRARQERL RQKQEEESLG QVTDQVEVNA QNSVPDEEAK TTTTNTQVEG DDEAAFLERL ARREERRQKR LQEALERQKE FDPTITDASL SLPSRRMQND TAENETTEKE EKSESRQERY EIEETETVTK SYQKNDWRDA EENKKEDKEK EEEEEEKPKR GSIGENQIKD EKIKKDKEPK EEVKSFMDRK KGFTEVKSQN
-
Kreuzreaktivität
- Human
-
Produktmerkmale
- Polyclonal Antibodies
-
Aufreinigung
- Affinity purification
-
Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CALD1 (NP_004333.1).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB,1:500 - 1:2000
-
Kommentare
-
HIGH QUALITY
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
-
Andere Bezeichnung
- CALD1
-
Hintergrund
- This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.,CALD1,CDM,H-CAD,HCAD,L-CAD,LCAD,NAG22,caldesmon,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,Cardiovascular,Heart,Contractility,CALD1
-
Molekulargewicht
- 61 kDa/62 kDa/64 kDa/65 kDa/93 kDa
-
Gen-ID
- 800
-
UniProt
- Q05682
-
Pathways
- Myometrial Relaxation and Contraction
Target
-