C4BPB Antikörper (AA 18-251)

Produktnummer ABIN6137775

Der Kaninchen Polyklonal Anti-C4BPB-Antikörper wurde für WB validiert. Er ist geeignet, C4BPB in Proben von Human zu detektieren.

Kurzübersicht für C4BPB Antikörper (AA 18-251) (ABIN6137775)

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C4BPB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-C4BPB Antikörper

Bindungsspezifität: AA 18-251

Sequenz: SDEHCPELPP VDNSIFVAKE VEGQILGTYV CIKGYHLVGK KTLFCNASKE WDNTTTECRL GHCPDPVLVN GEFSSSGPVN VSDKITFMCN DHYILKGSNR SQCLEDHTWA PPFPICKSRD CDPPGNPVHG YFEGNNFTLG STISYYCEDR YYLVGVQEQQ CVDGEWSSAL PVCKLIQEAP KPECEKALLA FQESKNLCEA MENFMQQLKE SGMTMEELKY SLELKKAELK AKLL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 18-251 of human C4BPB (NP_001017364.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu C4BPB

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Andere Bezeichnung: C4BPB

Hintergrund: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.,C4BPB,C4BP,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,C4BPB

Molekulargewicht: 28 kDa

Gen-ID: 725

UniProt: P20851

Pathways: Komplementsystem