Bystin-Like Antikörper (AA 120-280)

Produktnummer ABIN6137672

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Bystin-Like in WB, IF und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Bystin-Like Antikörper (AA 120-280) (ABIN6137672)

Target: Bystin-Like (BYSL)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Bystin-Like Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-Bystin-Like Antikörper

Bindungsspezifität: AA 120-280

Sequenz: HAEVVVDPED ERAIEMFMNK NPPARRTLAD IIMEKLTEKQ TEVETVMSEV SGFPMPQLDP RVLEVYRGVR EVLSKYRSGK LPKAFKIIPA LSNWEQILYV TEPEAWTAAA MYQATRIFAS NLKERMAQRF YNLVLLPRVR DDVAEYKRLN FHLYMALKKA L

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human BYSL (NP_004044.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Bystin-Like

Target: Bystin-Like (BYSL)

Andere Bezeichnung: BYSL

Hintergrund: Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi.,BYSL,BYSTIN,bystin,Epigenetics & Nuclear Signaling,RNA Binding,BYSL

Molekulargewicht: 49 kDa

Gen-ID: 705

UniProt: Q13895

Pathways: Cellular Response to Molecule of Bacterial Origin