BMP15 Antikörper (AA 143-392)

Produktnummer ABIN6137593

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BMP15 in WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für BMP15 Antikörper (AA 143-392) (ABIN6137593)

Target: BMP15 (Bone Morphogenetic Protein 15 (BMP15))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-BMP15 Antikörper

Bindungsspezifität: AA 143-392

Sequenz: LTRFNLSCHV EPWVQKNPTN HFPSSEGDSS KPSLMSNAWK EMDITQLVQQ RFWNNKGHRI LRLRFMCQQQ KDSGGLELWH GTSSLDIAFL LLYFNDTHKS IRKAKFLPRG MEEFMERESL LRRTRQADGI SAEVTASSSK HSGPENNQCS LHPFQISFRQ LGWDHWIIAP PFYTPNYCKG TCLRVLRDGL NSPNHAIIQN LINQLVDQSV PRPSCVPYKY VPISVLMIEA NGSILYKEYE GMIAESCTCR

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 143-392 of human BMP15 (NP_005439.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu BMP15

Target: BMP15 (Bone Morphogenetic Protein 15 (BMP15))

Andere Bezeichnung: BMP15

Hintergrund: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure.,BMP15,GDF9B,ODG2,POF4,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,Cytokines,NF-kB Signaling Pathway,Stem Cells,Germline Stem Cells,Cardiovascular,Angiogenesis,BMP15

Molekulargewicht: 45 kDa

Gen-ID: 9210

UniProt: O95972